now that you mention it, the drop down box options are dependent upon which audio driver is selected. I should of realized that. At any rate, I do have the ASIO4ALL installed, but I guess I didn't explore enough before I posted that O.o Thanks for the assist though, after I read your post, I opened up audition and sure enough, I was able to select both my main sound card as well as my USB mic and use one for input, and the other for output.